Additional Information

Description

Vancomycin 500 mg 10 mL 10/Bx is a sterile powder for injection, used as a glycopeptide antibiotic to treat severe bacterial infections caused by gram-positive organisms. It is particularly effective against methicillin-resistant Staphylococcus aureus (MRSA), Clostridioides difficile-associated diarrhea, and other resistant bacterial strains. The medication is primarily administered intravenously.

The mechanism of action of vancomycin involves inhibiting bacterial cell wall synthesis by binding to the D-alanyl-D-alanine terminus of the peptidoglycan precursors. This action prevents the cross-linking of cell wall components, leading to bacterial lysis and death. Vancomycin is bactericidal and works specifically against gram-positive organisms, including resistant strains such as Enterococcus and Streptococcus species.

Vancomycin is generally reserved for serious infections to reduce the risk of developing bacterial resistance. Side effects may include nephrotoxicity, ototoxicity, and infusion-related reactions, such as "red man syndrome," characterized by flushing and itching. To minimize adverse effects, the infusion should be administered slowly, typically over 60 minutes.