Additional Information

Description

Levophed (Norepinephrine Bitartrate) 1 mg/mL is a sterile, single-dose vial formulation used as a potent vasopressor to treat acute hypotension and shock. It is intended for intravenous administration and requires careful dilution before use. The drug acts by stimulating alpha-adrenergic receptors in vascular smooth muscle, leading to vasoconstriction and an increase in blood pressure.

This medication is primarily utilized in critical care settings for conditions such as septic shock, neurogenic shock, or hypotension unresponsive to fluid resuscitation. Its rapid onset of action and strong vasoconstrictive effects make it an essential treatment for life-threatening cardiovascular conditions. It is typically administered via a central line to reduce the risk of extravasation and related tissue damage.

Levophed is supplied in single-dose 4 mL vials containing 1 mg of norepinephrine per mL, free from preservatives. It must be diluted before administration in a dextrose-containing solution to prevent oxidation. The diluted solution should be protected from light and used within 24 hours.