Additional Information

Description

Dexamethasone, a synthetic corticosteroid, is utilized for its potent anti-inflammatory and immunosuppressive properties. It is often administered in conditions requiring rapid reduction of inflammation and management of immune responses. The injectable formulation is available in a 10 mg/mL concentration, with a volume of 1 mL, commonly used in acute conditions such as severe allergies, adrenal insufficiency, and cerebral edema.

The drug works by inhibiting the release of substances that promote inflammation, such as prostaglandins, while also modulating the immune system. Dexamethasone binds to glucocorticoid receptors in the cytoplasm of target cells, leading to alterations in gene expression that reduce the production of pro-inflammatory cytokines and increase the synthesis of anti-inflammatory proteins.

Dexamethasone is indicated for conditions like allergic reactions, inflammation, autoimmune diseases, and certain types of cancer. It is also used to prevent or treat nausea and vomiting associated with chemotherapy. The 10 mg/mL concentration provides a strong therapeutic effect with a rapid onset of action when administered intravenously or intramuscularly.