Additional Information

Description

Desflurane is a volatile halogenated anesthetic agent used primarily for the induction and maintenance of general anesthesia in surgical procedures. It is delivered through a calibrated vaporizer as part of an inhalation anesthetic system. The active ingredient is desflurane, which is a highly fluorinated compound that enables rapid onset and recovery due to its low blood-gas partition coefficient.

Desflurane is indicated for use in adults and children, with careful monitoring required due to its potential to cause airway irritation, particularly during induction. It is often preferred for its predictability in maintaining stable anesthesia levels and its reduced accumulation in the body, which minimizes prolonged sedation postoperatively.

The mechanism of action involves the enhancement of inhibitory neurotransmitter activity and depression of excitatory neurotransmitter activity in the central nervous system. This leads to a reversible loss of consciousness and sensation. Desflurane is well-known for its precision in titration, providing anesthesiologists with a high degree of control over anesthesia depth during procedures.